The Game Changer: Targeting Genetic Modifiers to Stop Huntington’s Disease

April 24, 2025, 12-1pm ET

Gabriel Balmus, PhD
University of Cambridge, United Kingdom

Zachariah L. McLean, PhD
Massachusetts General Hospital, Harvard Medical School, Boston, MA

Followed by Q&A

About the Speakers

Gabriel Balmus, PhD
Group Leader, UK Dementia Research Institute, University of Cambridge, UK

Interested in the mechanisms controlling the maintenance of nuclear and mitochondrial genomes in mature neurons, Prof Gabriel Balmus joined the UK Dementia Research Institute at the University of Cambridge in 2018. As Group Leader, Gabriel brings his wealth of expertise to research genomic instability in neurodegenerative diseases.

Zachariah L. McLean, PhD
Instructor in Investigation, Massachusetts General Hospital, Harvard Medical School, Boston; Broad Institute, Boston

Dr. Zach McLean is an Instructor in Investigation at the Center for Genomic Medicine at Massachusetts General Hospital, Harvard Medical School, and the Broad Institute. He works in the lab of Professor James Gusella where his research focuses on in vitro modelling for genetic modifiers of Huntington’s disease.

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