Insights from CAG Repeats for HD Therapies

About the Speakers

Jong-Min Lee, PhD
Associate Professor, Massachusetts General Hospital and Harvard Medical School

Dr. Jong-Min Lee is an Associate Professor at the Massachusetts General Hospital and Harvard Medical School, specializing in human genetics with a focus on identifying genetic modifiers of Huntington’s disease. As a member of the GeM-HD Consortium, Dr. Lee’s team has uncovered that DNA repair genes involved in CAG repeat instability, play a critical role in modifying the age of onset and other key phenotypes associated with Huntington’s Disease. Currently, Dr. Lee’s laboratory is translating these genetic insights into novel treatment strategies for Huntington’s disease.

Chris Kay, PhD
Research Associate, Hayden Lab, University of British Columbia

Dr. Chris Kay is a geneticist and molecular biologist at the University of British Columbia in Vancouver, Canada. He studies genetic modifiers of Huntington’s disease for discovery and understanding of new therapeutic targets. His research also focuses on the significance of somatic CAG repeat instability in HD, and how the gene that causes HD varies between patients around the world.